In the New England Journal of Medicine, Dr. Donald R. Johns reported what appeared to be a connection between a case of migraine and the consumption of large amounts of a beverage containing NutraSweet™. A thirty-one-year-old woman with a known history of well-controlled migraine headaches began drinking six to eight 12-ounce cans of diet cola sweetened with NutraSweet, 15 tablets of aspartame, and other foods containing aspartame (approximately 100 to 1500 mg) daily. About two hours after ingesting the drinks, she noticed stomach upset and a throbbing headache. When taken off aspartame, she noticed steady improvement and eventually the headaches disappeared altogether. Dr. Donald R. Johns
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