I know this is only anecdotal but my sister at age 32 with no neurological symptoms her whole life had two grand mal seizures in the space of a few days. This was after a summer of drinking large quantities of Crystal Light, a lemonade mix sweetened with NutraSweet. No antecedents or siblings have ever had such symptoms. This was several years ago, but we (my family) eventually decided to lay off Aspartame. I guess I do believe that there are people with a heightened sensitivity to Aspartame. It is an easy thing to avoid.
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