Category Archives: Aspartame Research Articles

Aspartame Research Articles© #018 – My Aspartame Experiment: Report from a Private Citizen – April 15, 2020, Paperback Book from Amazon

In My Aspartame Experiment: Report from a Private Citizen, author Victoria Inness-Brown recounts her controversial 2-1/2 year study of the effects of the artificial sweetener aspartame. Found in packets of NutraSweet or Equal, the sweetener is ingested by an estimated … Continue reading

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Aspartame Research Articles© #017 – Chronic aspartame intake causes changes in the trans-sulphuration pathway, glutathione depletion and liver damage in mice

Isabela Finamor, Salvador Pérez, Caroline A. Bressan, Carlos E. Brenner, Sergio Rius-Pérez, Patricia C. Brittes, Gabriele Cheiran, Maria I. Rocha, Marcelo da Veiga, Juan Sastre, and Maria A. Pavanato Redox Biol. 2017 Apr; 11: 701–707. Published online 2017 Feb 1. doi: 10.1016/j.redox.2017.01.019 PMCID: PMC5300302 … Continue reading

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Aspartame Research Articles© #016 – Increasing Brain Tumor Rates: Is There a Link to Aspartame?

Journal of Neuropathology & Experimental Neurology: November 1996 Oney, John W. MD; Farber, Nuri B.; Spitznagel, Edward; Robins, Lee N. Abstract In the past two decades brain tumor rates have risen in several industrialized countries, including the United States. During … Continue reading

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Aspartame Research Articles© #015 – Life-Span Exposure to Low Doses of Aspartame Beginning during Prenatal Life Increases Cancer Effects in Rats

Environ Health Perspect. 2007 September; 115(9): 1293–1297. Published online 2007 June 13. doi:  10.1289/ehp.10271, PMCID: PMC1964906 Morando Soffritti, Fiorella Belpoggi, Eva Tibaldi, Davide Degli Esposti, and  Michelina Lauriola Cesare Maltoni Cancer Research Center, European Ramazzini Foundation of Oncology and Environmental … Continue reading

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Aspartame Research Articles© #014 – Effects of Artificial Sweeteners on Body Weight, Food and Drink Intake

Acta Physiol Hung. 2010 Dec;97(4):401-7. doi: 10.1556/APhysiol.97.2010.4.9. Polyák E, Gombos K, Hajnal B, Bonyár-Müller K, Szabó S, Gubicskó-Kisbenedek A, Marton K, Ember I. Faculty of Health Sciences University of Pécs Department of Nutritional Sciences and Dietetics, Institute of Physiotherapy and … Continue reading

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Aspartame Research Articles© #013 – Possible Neurologic Effects of Aspartame, a Widely Used Food Additive

Environ Health Perspect. 1987 Nov;75:53-7. Maher TJ, Wurtman RJ. Department of Pharmacology, Massachusetts College of Pharmacy, Boston 02115. Abstract The artificial sweetener aspartame (L-aspartyl-L-phenylalanyl-methyl ester), is consumed, primarily in beverages, by a very large number of Americans, causing significant elevations … Continue reading

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Aspartame Research Articles© #012 – Cytotoxic Effects of Methanol, formaldehyde, and formate on Dissociated Rat Thymocytes: a Possibility of Aspartame Toxicity

Cell Biol Toxicol. 2002;18(1):43-50. Oyama Y, Sakai H, Arata T, Okano Y, Akaike N, Sakai K, Noda K. Laboratory of Cellular Signaling, Faculty of Integrated Arts and Sciences, The University of Tokushima, Japan. oyama@ias.tokushima-u.ac.jp Abstract Aspartame is a widely used … Continue reading

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Aspartame Research Articles© #011 – The Effect of L-cysteine and Glutathione on Inhibition of Na+, K+-ATPase Activity by Aspartame Metabolites in Human Erythrocyte Membrane

Eur J Clin Nutr. 2006 May;60(5):593-7. Schulpis KH, Papassotiriou I, Parthimos T, Tsakiris T, Tsakiris S. Institute of Child Health, Research Center, Aghia Sophia Children’s Hospital, Athens, Greece. Abstract BACKGROUND: Reports have implicated Aspartame (N-L-a-aspartyl-L-phenylalanine methyl ester, ASP) in neurological … Continue reading

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Aspartame Research Articles© #010 – The Effect of L-cysteine and glutathione on inhibition of Na+, K+-ATPase Activity by Aspartame Mn Human Erythrocyte Membrane

Eur J Clin Nutr. 2006 May;60(5):593-7. Schulpis KH, Papassotiriou I, Parthimos T, Tsakiris T, Tsakiris S. Institute of Child Health, Research Center, Aghia Sophia Children’s Hospital, Athens, Greece. Abstract BACKGROUND: Reports have implicated Aspartame (N-L-a-aspartyl-L-phenylalanine methyl ester, ASP) in neurological … Continue reading

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Aspartame Research Articles© #009 – l-Cysteine and Glutathione Restore the Modulation of Rat Frontal Cortex Na+, K+ -ATPase Activity Induced by Aspartame Metabolites

Food Chem Toxicol. 2008 Jun;46(6):2074-9. doi: 10.1016/j.fct.2008.01.050. Epub  2008 Feb 8. Simintzi I, Schulpis KH, Angelogianni P, Liapi C, Tsakiris S. Department of Physiology, Medical School, Athens University, P.O. Box 65257, GR-15401 Athens, Greece. Abstract BACKGROUND: Studies have suggested that … Continue reading

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Aspartame Research Articles© #008 – Effect of Long Term Intake of Aspartame on Antioxidant Defense Status in Liver

Food Chem Toxicol. 2011 Jun;49(6):1203-7. doi: 10.1016/j.fct.2011.02.019. Epub  2011 Mar 3. Abhilash M, Paul MV, Varghese MV, Nair RH. School of Biosciences, Mahatma Gandhi University, Kottayam, Kerala 686560, India. Abstract The present study evaluates the effect of long term intake … Continue reading

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Aspartame Research Articles© #007 – Effect of Aspartame on Oxidative Stress and Monoamine Neurotransmitter Levels in Lipopolysaccharide-treated Mice

Neurotox Res. 2012 Apr;21(3):245-55. doi: 10.1007/s12640-011-9264-9. Epub 2011 Aug 6. Abdel-Salam OM, Salem NA, Hussein JS. Department of Toxicology and Narcotics, National Research Centre, Tahrir St., Dokki, Cairo, Egypt. omasalam@hotmail.com Abstract This study aimed at investigating the effect of the … Continue reading

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Aspartame Research Articles© #006 – Long-term Consumption of Aspartame and Brain Antioxidant Defense Status

Drug and Chemical Toxicology, 2013 Apr;39(2):135-40. doi: 10.3109/01480545.2012.658403. Epub  2012 Mar 2. Abhilash M, Sauganth Paul MV, Varghese MV, Nair RH School of Biosciences, Mahatma Gandhi University, Kottayam, India Abstract The present study investigated the effect of long-term intake of … Continue reading

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Aspartame Research Articles© #005 – Effect of Chronic Exposure to Aspartame on Oxidative Stress in the Brain of Albino Rats.

Journal of Biosciences, 2012 Sep;37(4):679-88. Iyyaswamy A, Rathinasamy S. Department of Physiology, University of Madras, Sekkizhar campus, Taramani, Chennai 600 113, India. This study was aimed at investigating the chronic effect of the artificial sweetener aspartame on oxidative stress in … Continue reading

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Aspartame Research Articles© #004 – Studies on the Effects of Aspartame on Memory and Oxidative Stress in Brain of Mice

Eur Rev Med Pharmacol Sci. 2012 Dec;16(15):2092-101. Abdel-Salam OM, Salem NA, El-Shamarka ME, Hussein JS, Ahmed NA, El-Nagar ME Department of Toxicology and Narcotics, National Research Centre, Cairo, Egypt. omasalam@hotmail.com OBJECTIVE: The dipeptide aspartame (N-L-alpha-aspartyl-Lphenylalanine, 1-methyl ester; alpha-APM) is one … Continue reading

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Aspartame Research Articles© #003 – Intake of Artificially Sweetened Soft Drinks and Risk of Preterm Delivery: a Prospective Cohort Study in 59,334 Danish Pregnant Women

“The American Journal of Clinical Nutrition.” 2010 Sep;92(3):626-33. doi: 10.3945/ajcn.2009.28968. Epub  2010 Jun 30. Halldorsson TI, Strøm M, Petersen SB, Olsen SF Centre for Fetal Programming, Statens Serum Institut, Copenhagen, Denmark. lur@ssi.dk BACKGROUND: Sugar-sweetened soft drinks have been linked to … Continue reading

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Aspartame Research Articles© #002 – Does Aspartame Cause Human Brain Cancer?

Journal of Advancement in Medicine, Volume 4, Number 4, Winter 1991 H. J. Roberts, MD H.J. Roberts MD is Director, Palm Beach Institute for Medical Research.  He is Senior Active Staff, St. Mary’s Hospital and Good Samaritan Hospital, West Palm … Continue reading

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Aspartame Research Articles© #001 – Aspartame-induced Fibromyalgia, an Unusual but Curable Cause of Chronic Pain

Clin Exp Rheumatol. 2010 Nov-Dec;28(6 Suppl 63):S131-3. Epub 2010 Dec 22. Ciappuccini R, Ansemant T, Maillefert JF, Tavernier C, Ornetti P. Department of Rheumatology, Dijon University Hospital, Burgundy University, Faculty of Medicine, Dijon, France. Abstract We report for the first … Continue reading

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